We are proud to share the latest publication of the COMULIS network. In this literature review Balluff, Heeren and Race beautifully summarize image registration for aligning mass spectrometry imaging with clinically relevant imaging modalities.
An overview of image registration for aligning mass spectrometry imaging with clinically relevant imaging modalities.
Benjamin Balluff, Ron M.A. Heeren, Alan M. Race
Click here to find the full article.
In our recent publication, we established and implemented a cross-modality imaging (CMI) pipeline to characterize and compare bisphosphonate (BIS)-treated jawbones of Sprague-Dawley rats after tooth extraction after physical therapies. Each technique contributed unique parameters to the characterization of treated and untreated jawbones according to its strengths thus highlighting the importance of combined imaging techniques for biomedical research.
Cross-modality imaging of bisphosphonate-treated murine jawbones
Susanne Reier, Anna Turyanskaya, Patrick Heimel, Nikolaus Frischauf, Daria Meusburger, Thomas Heuser, Nicole Drexler, Ágnes Janovszky, Christina Streli, Paul Slezak, Birgit Plochberger, Peter Dungel, Andrea Szabóg and Andreas Walter
We are proud to announce the publication of two book chapters providing a comprehensive collection of the imaging techniques that are used in the biological and preclinical areas.
Imaging Modalities for Biological and Preclinical Research: A Compendium
Volume 1 & Volume 2
Edited by Andreas Walter, Julia G Mannheim and Carmel J Caruana
For a detailed description click HERE
Volume 1 focuses on ex-vivo imaging. It covers all available advanced and basic light and fluorescence microscopy modalities, X-ray, electron, atomic force and helium ion microscopy, dynamic techniques such as fluorescence recovery after photobleaching as well as spectroscopic techniques such as coherent Raman imaging or mass spectrometry imaging.
Volume 2 focuses on in vivo imaging methods, including intravital microscopy, ultrasound, MRI, CT and PET. Correlative multimodal imaging, (pre)clinical hybrid imaging techniques and multimodal image processing methods are also discussed. The volume concludes with a look ahead to emerging technologies and the future of imaging in biological and preclinical research.
Our recent publication about our efforts in building and consolidating a correlative multimodality imaging community (including public archiving of correlative imaging data) is published:
Correlative multimodal imaging: Building a community
Andreas Walter, Gerard J. Kleywegt, Paul Verkade. Methods in Cell Biology, January 2021
Abstract
Few would have thought that when Porter and colleagues used light microscopy to target their cell of interest to be analyzed in the electron microscope in the 1940s, that Correlative Imaging would develop into the thriving field it is today.
Even though the first use of Correlative Light Electron Microscopy (CLEM) was established in the 1940s, it is only since the year 2000 that there has been a real surge in the application of CLEM technology. The power of CLEM is recognized in the scientific community as evidenced by the growing number of publications and dedicated sessions at scientific meetings. The field is also broadening, incorporating a multitude of other techniques including preclinical research and diagnostics, and slowly but surely the overarching field of Correlative Multimodality Imaging (CMI) is taking its place as an established technique and a research area in its own right.
In this chapter, we will look at the initiatives that are being developed within the scientific world to build a coherent CMI community, with a particular emphasis on the developments in Europe. To achieve this aim, the community will need to design mechanisms for the interdisciplinary exchange of knowledge and benefits, set up training schemes, and develop standards for CMI technology and its data.
Correlated Multimodal Imaging in Life Sciences: Expanding the Biomedical Horizon
Andreas Walter, Perrine Paul-Gilloteaux, Birgit Plochberger, Ludek Sefc, Paul Verkade, Julia G. Mannheim, Paul Slezak, Angelika Unterhuber, Martina Marchetti-Deschmann, Manfred Ogris, Katja Bühler, Dror Fixler, Stefan H. Geyer, Wolfgang J. Weninger, Martin Glösmann, Stephan Handschuh and Thomas Wanek. Frontiers in Physics, 09 April 2020